NEURAL MECHANISMS UNDERLYING THE COMPUTATION OF HIERARCHICAL TREE STRUCTURES IN MATHEMATICS.




MARC, a novel modular chimeric antigen receptor, improves T cell-based cancer immunotherapies by preventing early T cell exhaustion and enhancing persistence

Background Chimeric antigen receptor T cell (CAR-T)-based immunotherapies have reshaped the therapeutic landscape of cancer treatment, in particular for patients afflicted with leukemia.However, defects in CAR behaviors and clinical complications have hindered their widespread application across diverse cancer types.Chief among these defects is hig

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